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该書自1951年出版以来至1956年已經是第6版第16次印刷了。由出版及印刷次數来看,該書是很受一般读者欢迎的,其间經过編著者几次修訂,使該書益趋于完善,諸多优点,在此不拟贅述。但尽管如此,該着也有一定缺点和欠妥之处,我們現將該書第六版中主要缺点及欠妥之处举列于下,供讀者及該書作者参考。据我們最近了解,讀書新版(第七版)已經出版,其中对本文內所提各点多已改正,但为了供購有該書第六版的读者参考,我們觉得發表本文仍然是有一定的意义的。该書61页上数6行写道:“磺胺药……服药期間要避免服难于消化的蛋白質、鹽类瀉剂、砜类催眠药(以免产生硫化氫而發绀)”。服用磺胺类药时,有些患者會发生发绀現象(氨苯磺胺比较多見)。过去認为这种现象,是由于磺胺类药物,在体内可以使硫化物和血色蛋白結合成为硫化血色蛋白或定氧血色蛋白所致,所以往昔临床上凡服用磺胺药的患者即禁食鷄卵、葱蒜(因含硫化物)及硫酸鹽类瀉药等。但应想到,硫酸鎂较难被消化道所吸收,故亦难發生血液变化。近年来诸多文献报导,这种能引起發绀的硫化血色蛋白,在磺胺治疗期內,虽然在血中可以出現,但为量極少,与发绀的产生无多关系。发绀的主要原因,是由于磺胺化合物与还原血色蛋白結合,形成一种未知的有色物質所致。因此服用磺胺类药物时可以不必禁用蛋白質及鹽类瀉药。该書67頁比較详细的介紹了“另一种延長青霉素时效的流行制剂——苏联医学界推荐的青霉素匹拉米董(即氨基比林)液……”並詳尽介紹了該制剂的配制方法。如所周知:發明这种方法的苏联罗方諾夫等三位学者,已綜合了很多病例,和他們自己研究材料,又再次發表文章,已否定这种方法。苏
This book has been printed for the 16th edition since its publication in 1951 to 1956. From the perspective of the number of publications and printing, the book is very popular with the general readers. During this period, several revisions have been made by the editors to make the book more and more prosperous, with many merits. We will not go into details here. Nevertheless, there are some shortcomings and defects in this book. We will now list the major shortcomings and defects in the sixth edition for your reference of the reader and the author of the book. As far as we have learned recently, the new edition of Reading (Seventh Edition) has been published, of which many of the points mentioned in this article have been corrected. However, for reference of readers who purchased the sixth edition of the book, we feel that there is still a certain amount of published text meaningful. The book six pages on the 6th wrote: “Sulfa drugs ... to avoid taking difficult to digest proteins, salt laxatives, sulfone hypnotics (to avoid cyanosis and cyanosis)”. When taking sulfonamides, some patients will develop cyanosis (more than ammonia sulfonamides). In the past that this phenomenon is due to sulfa drugs in the body can make sulfides and hemoglobin protein into sulfated hemoglobin or oxidized hemoglobin, so in the past where patients taking sulfa drugs that fasting chicken eggs , Onion garlic (due to sulfide) and sulfate laxatives. However, it should be remembered that magnesium sulfate is more difficult to be absorbed by the digestive tract, so it is difficult for blood to change. In recent years, many literatures reported that this can cause cyanosis of the blood sulfide protein in the sulfa treatment period, although it can occur in the blood, but the amount of very little, and the cyanosis is not linked. The main reason for cyanosis is due to sulfonamide compounds and reducing hemoglobin binding, the formation of an unknown colored material due. Therefore, taking sulfonamides do not have to disable protein and salt laxatives. The book contains a more detailed introduction on page 67. “Another popular formulation that prolongs the duration of penicillin-the penicillin-pirarubi (ie, aminopyrine) solution recommended by the Soviet medical community ...” The preparation method. As we all know, the three scholars, such as the Soviet Union Rozanov, who invented this method, have synthesized many cases, and have researched the materials themselves again, and published an article once again denying this method. Su