Role of a homodimerization enhanced Oct4 in reprogramming to pluripotency

来源 :第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 | 被引量 : 0次 | 上传用户：Crownless

【摘要】

：

Oct4 heterodimerizes with Sox2 to direct a gene expression program establishing pluripotency.Oct4 also possess a lesser-known ability to homodimerize on palindromic DNA sequences.

【作者】

：

Xiaoxiao Yang Veeramohan Veerapandian Vikas Malik Fenggong cui Yan Xu Longqi Liu Calista Keow Leng Ng Stepan Jerabek Andrew Hutchins Vlad Cojocaru Miguel A Esteban Hans Robert Sch(o)ler Ralf Jauch

【机构】

：

Genome Regulation Laboratory,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Scien

【出处】

：

第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会

【发表日期】

：

2015年3期

【关键词】

：

Oct4 homodimerization reprogramming pluripotency

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　　Oct4 heterodimerizes with Sox2 to direct a gene expression program establishing pluripotency.Oct4 also possess a lesser-known ability to homodimerize on palindromic DNA sequences.

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Role of a homodimerization enhanced Oct4 in reprogramming to pluripotency

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