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  5. Identifying and characterizing leukemia-initiating cells in adult B cell acute lymphoblastic leukemi

Identifying and characterizing leukemia-initiating cells in adult B cell acute lymphoblastic leukemi

来源 :第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 | 被引量 : 0次 | 上传用户：wapp592
【摘 要】
：
The existence and identification of leukemia stem cells in adult acute B lymphoblastic leukemia(B-ALL)remain controversial.We examined whether adult B-ALL is hierarchically organized into phenotypical
【作 者】
：
Zhiwu Jiang Manman Deng Bing Xu Peng Li 
【机 构】
：
Key Laboratory of Regenerative Biology,South China Institute for Stem Cell Biology and Regenerative
【出 处】
：
第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会
【发表日期】
：
2015年3期
【关键词】
：
B-ALL leukemia stem cell heterogeneity microenvironment xenograft 
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　　The existence and identification of leukemia stem cells in adult acute B lymphoblastic leukemia(B-ALL)remain controversial.We examined whether adult B-ALL is hierarchically organized into phenotypically distinct subpopulations of leukemogenic and non-leukemogenic cells or whether most B-ALL cells retain leukemogenic capacity,irrespective of their immunophenotypes.
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