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  5. The opposite function of Setdb1 in pluripotency maintainance and reestablishment

The opposite function of Setdb1 in pluripotency maintainance and reestablishment

来源 :第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 | 被引量 : 0次 | 上传用户：uj_mosquito12
【摘 要】
：
Stedb1,known as a Histone H3 Lys9(H3K9)methyltransferase,plays an important role in maintaining embryonic stem(ES)cell identity.Paradoxically,its reported that Stedb1(Eset)can act as a barrier in plur
【作 者】
：
Kaixin Wu He Liu Jiekai Chen 
【机 构】
：
Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,China
【出 处】
：
第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会
【发表日期】
：
2015年3期
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　　Stedb1,known as a Histone H3 Lys9(H3K9)methyltransferase,plays an important role in maintaining embryonic stem(ES)cell identity.Paradoxically,its reported that Stedb1(Eset)can act as a barrier in pluripotency reestablishment to blot reprogram in a pre-iPSc state.
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