PULMONARY TOXICITY FOLLOWING INTRATRACHEAL INSTILLATION STUDY OF NICKEL OXIDE NANOPARTILCES AGGLOMER

• 作 者: YasuoMORIMOTO;ByeongWooLEE;EtsushiKURODA;IsamuTANAKA;MasamiHIROHASHI;MasanoriHorie;AkiraOGAMI;TakakoOYABU;ToshihikoMYOJO;MasayoshiHASHIBA;YoheiMIZUGUCHI;TatsunoriKAMBARA;
• 机 构: University of Occupational and Environmental Health,Japan.Kitakyushu,Fukuoka 807-8555,Japan
• 出 处: The 22nd China-Korea-Japan Joint Conference on Occupational
• 发表日期: 2011年期

　　In order to investigate whether or not nanoparticles have an effect of neutrophil inflammation on the lung, we examined the expression of cytokine-induced neutrophil chemoattractants (CINCs) family in rat lung by intratracheal instillation study of nickel oxide nanoparticles agglomerates with the micron-level.The count median diameter of nickel oxide nanoparticle agglomerates suspended in saline was 1.34 m (8.41nm of weighted average surface primary diameter).