【摘 要】
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In this report,we are introducing our recent progress for gradient generation on Microfluidic Paper Analytical Devices(μPADs),which is a hot research frontiers of point of care test(POCTs).An abnormal
【机 构】
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State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of
【出 处】
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中国化学会第十二届全国微全分析系统学术会议、第七届全国微纳尺度生物分离分析学术会议、第七届国际微流控学学术论坛
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In this report,we are introducing our recent progress for gradient generation on Microfluidic Paper Analytical Devices(μPADs),which is a hot research frontiers of point of care test(POCTs).An abnormal phenomenon of liquid motion was found on paper capillary empowered μPADs.With this principle,we can form a gradient of liquid reagent on paper chip.The gradient generation is much faster than traditional μPADs,and it can be arrayed,which is conducive to high-throughput analysis.In the experiment,the paper capillary empowered μPADs were fabricated by carving on paper and bonding with tape[1.When liquid was added sequentially,gradient was generated fast.With a special folded chip structure,we were able to create an array of liquid gradients.The same column of liquid reagent remained uniform by transport between the overlapping layers.The concentration of metal ions were detected on the paper capillary empowered μPADs,predicted the availability of this method in actual testing.
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