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  5. Sleep and EEG as biological markers in animal models of Huntington's disease

Sleep and EEG as biological markers in animal models of Huntington's disease

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：skiau2548
【摘 要】
：
Although abnormal circadian rhythmicity has been demonstrated in both human patients and in rodent models of Huntingtons disease (HD), a comprehensive description of sleep and electroencephalogram (EE
【作 者】
：
Sandor KANTOR Lajos SZABO Janos VARGA Marc CUESTA Jennifer MORTON 
【机 构】
：
Department of Physiology, Development and Neuroscience, University of Cambridge,Cambridge, CB2 3DY,
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
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Although abnormal circadian rhythmicity has been demonstrated in both human patients and in rodent models of Huntingtons disease (HD), a comprehensive description of sleep and electroencephalogram (EEG) changes has never been conducted.Here we studied sleep and EEG disturbances in a transgenic mouse model of HD (R6/2 mice).
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