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Widely used in building industry,Magnesium phosphate cements(MPCs)can also be considered in biomedical areas because of its properties such as fast setting,early strength acquisition and high viscosity.The clinical application of MPCs,however,is restricted by some of its other features such as highly exothermic setting reaction and the release of potentially harmful ammonia or ammonium ions.At present,the research of MPCs is limited in examining the grain size of the MgO and calcining technology which can decide the reaction in Liquid-solid interface.There are few studies in Regulating MgO solid phase reactions actives to decide the reaction speed in Liquid-solid interface.