蛋白诱导生成的新一代干细胞的心肌再生能力和对梗死后心功能的改善作用

来源 :第17届中国南方国际心血管病学术会议 | 被引量 : 0次 | 上传用户：liubifeng1392

【摘要】

：

目的心肌梗死后的细胞移植治疗是目前新兴的研究热点.第一代细胞移植治疗是采用未经处理的骨髓来源的间充质干细胞(BMSCs)直接治疗心肌梗死,心肌再生能力低而疗效不确切.随着心脏干/祖细胞在心肌再生中的作用日益得到重视,人们分离培养心脏干细胞,或者将BMSCs在细胞因子的作用下生成心脏谱系的干细胞作为第二代移植细胞,用于心梗后的细胞治疗,但生成的心脏干细胞数量有限,不易大量扩增用于临床.

【作者】

：

李晓红姜霖吴岳恒符永恒张梦珍谭虹虹肖静杨翔宇单志新王建军余细勇

【机构】

：

广东省人民医院,广东省医学科学院,广东省心血管病研究所,医学研究中心美国韦恩州立大学医学院

【出处】

：

第17届中国南方国际心血管病学术会议

【发表日期】

：

2015年9期

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蛋白诱导生成的新一代干细胞的心肌再生能力和对梗死后心功能的改善作用

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