Tumor Cell-activated CARD9 Signaling Contributes to Metastasis-associated Macrophage Polarization

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户：antoney

【摘要】

：

Tumor progression and metastasis are affected by dynamic changes in the specific phenotypes of macrophage subpoputations; however, the mechanisms by which tumor cell modulates macrophage polarization

【作者】

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Min Yang Jie Du

【机构】

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Beijing Anzhen Hospital Capital Medical University China

【出处】

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2014第七届世界癌症大会

【发表日期】

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2014年12期

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　　Tumor progression and metastasis are affected by dynamic changes in the specific phenotypes of macrophage subpoputations; however, the mechanisms by which tumor cell modulates macrophage polarization remain incompletely understood.CARD9 (Caspase recruitment domain-containing protein 9) is a central adaptor protein of innate immune responses to extracellular pathogens.

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Tumor Cell-activated CARD9 Signaling Contributes to Metastasis-associated Macrophage Polarization

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