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  5. Effects of all trans-retinoic acid or nitric oxide on the differentiation of neural stem cells/neura

Effects of all trans-retinoic acid or nitric oxide on the differentiation of neural stem cells/neura

来源 :中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the | 被引量 : 0次 | 上传用户：limihu93
【摘 要】
：
Neural stem cells/neural precursors (NSCs/NPs) may play important roles in transplantation therapies for neurodegenerative diseases,but the mechanism of NSCs/NPs differentiation is poorly understood.H
【作 者】
：
Zhe-Yan SA Hong GAO Shan GONG Li-Dong SHAN Xing-Hong JIANG 
【机 构】
：
Department of Neurobiology, Laboratory of Aging and Nervous Diseases, School of Medicine, Soochow Un
【出 处】
：
中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
【发表日期】
：
2007年12期
【关键词】
：
neural stem cells/neural precursors ATRA nitric oxide DETA/NO L-NAME differentia 
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　　Neural stem cells/neural precursors (NSCs/NPs) may play important roles in transplantation therapies for neurodegenerative diseases,but the mechanism of NSCs/NPs differentiation is poorly understood.Here,we explored the effects of ATRA (all trans-retinoic acid) or NO (nitric oxide) on the differentiation of NSCs//NPs from neonatal rats in vitro.The secondary neurospheres from subventricular zone (SVZ) region of neonatal Sprague Dawley rats were used to observe the effects of ATRA or NO on differentiation and the differentiated cells were identified by immunocytochemistry.
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