【摘 要】
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Objectives:Wu-Ling-San (WLS) formula has been proved to prevent calcium oxalate nephrolithiasis both in vitro and in vivo.In this study,we examined the efficacy of WLS formula prophylaxis for preventi
【机 构】
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Department of Urology,Chang Bing Show Chwan Memorial Hospital;Department of Life Science,National Ch
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Objectives:Wu-Ling-San (WLS) formula has been proved to prevent calcium oxalate nephrolithiasis both in vitro and in vivo.In this study,we examined the efficacy of WLS formula prophylaxis for preventing recurrent calcium oxalate nephrolithiasis.Methods:This was a prospective clinical study that evaluated the 24-hour urine parameters of 39 patients with kidney stones.All patients had a history of recurrent calcium oxalate nephrolithiasis.The patients were asked to drink enough fluid to urinate at least 2 L daily during the study period.A 24-hour urine collection was performed to establish the baseline levels of multiple urinary parameters before taking the medicine.The patients were randomized and divided into two groups.The medication group took 2 grn WLS formula three times daily for 1 month.The control group took 2 gm placebo three times daily for 1 month.A 24-hour urine collection was performed to evaluate multiple urinary parameters from all patients during the study period.Serum electrolytes,liver and renal functions were also determined.
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