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  5. Effect on HIF-1α and Apoptosis in Rat Hippocampal Neurons Exposed Intermittent Hypoxia

Effect on HIF-1α and Apoptosis in Rat Hippocampal Neurons Exposed Intermittent Hypoxia

来源 :The Third Internaitional Conference on Respiratory Diseases( | 被引量 : 0次 | 上传用户：chuengwang
【摘 要】
：
Objective Obstructive sleep apnea (OSA) can cause cognitive dysfunction.Exposure to intermittent hypoxia, such as encountered in OSAHS, is marked by neurodegenerative changes in rat brain.We investiga
【作 者】
：
Tan Jin Zhang Qiang Fang Yunyun Li Lulu 
【机 构】
：
From the Ministry of Health and Medical,Tianjin Institute of geriatrics,Tianjin Medical University G
【出 处】
：
The Third Internaitional Conference on Respiratory Diseases(
【发表日期】
：
2013年2期
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　　Objective Obstructive sleep apnea (OSA) can cause cognitive dysfunction.Exposure to intermittent hypoxia, such as encountered in OSAHS, is marked by neurodegenerative changes in rat brain.We investigated the change of HIF-1α and apoptosis in rats hippocampal neurons exposed to intermittent hypoxia.The aim is to explore the mechanism of sleep apnea-induced nervous-system injury.
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