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Cognitive control consists of mental operations that coordinate thoughts and actions under uncertainty in accordance with goal-directed behavior.It is necessary for the executive functions of conflict resolution,response inhibition,task-set switching,working memory,and decision making,among others.Although there is emerging evidence of a common cognitive control network across many cognitive domains,this network has been partially linked to some functions of cognitive control,such as conflict processing,which is a special case of increased uncertainty.In this study,we employed large-scale meta-analysis of functional neuroimaging studies involving manipulations of uncertainty to examine whether a common cognitive control network(CCN)is involved in uncertainty processing across various cognitive domains.We found that in addition to unique modality-and domain-specific regions,there was common activation in areas typically associated with the frontoparietal network(frontal eye fields and areas near/along the intraparietal sulcus)as well as dorsolateral prefrontal cortex,the cingulo-opercular network(anterior cingulate cortex/supplementary motor area,anterior insular cortex,and thalamus),and striatum(caudate and putamen).These results demonstrate that these regions and networks constitute the CCN,which supports the modality-and domain-general uncertainty resolution in higher-order cognitive functions by interacting with modality-and domain-specific brain regions and networks.