Control of fungal morphology for improved production of a novel antimicrobial alkaloid by marine-der

• 作 者: JunYang[1]Rui-HuaJiao[2]Ling-YunYao[1]Wen-BoHan[2]Yan-HuaLu[3]Ren-XiangTan[2]
• 机 构: State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Sha
• 出 处: 2015年上海市研究生学术论坛(生物化工)
• 发表日期: 2015年期

　　Curvulamine is a novel alkaloid with strong antimicrobial activity produced by the marine-derived fungus Curvularia sp.IFB-Z10.In this work, the effect of different carbon and nitrogen source on the cell growth and curvulamine production were firstly investigated.Different types of morphologies were formed and pellet-like growth of fungi was found positive for the curvulamine formation, and sucrose, yeast extract and sodium nitrate revealed to be most suitable for curvulamine formation.