CPUY201112,a novel synthetic small-molecule compound as inhibitor of heat shock protein Hsp90,induce

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：damitanqq

【摘要】

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【作者】

：

Xiao-Li Xu Qi-chao Bao Jian-Min Jia Fang Liu Xiao-Ke Guo Ming-ye Zhang Jin-lian Wei Meng-chen Lu Li-li Xu Xiao-Jin Zhang Hao-Peng Sun Qi-Dong You

【机构】

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Jiangsu Key Laboratory of Drug Design and Optimization,China Pharmaceutical University,Nanjing,21000

【出处】

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2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

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2015年3期

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　　Heat shock protein 90(Hsp90)is highly expressed in many tumor cells and is associated with the maintenance of malignant phenotypes.Targeting Hsp90 has shown some therapeutic success in solid and hematological malignancies,inspiring more work to identify new Hsp90 inhibitors with improved clinical efficacy.

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CPUY201112,a novel synthetic small-molecule compound as inhibitor of heat shock protein Hsp90,induce

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