【摘 要】
：
Type 1 diabetes (T1D) results from the immune-mediated destruction of insulin-producing B-cells by autoreactive CD4 and CD8 T cells.T1D ranks as the most common chronic childhood disease and its preva
【机 构】
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Department of Endocrinology & Diabetes University Campus Bio-Medico Italy
【出 处】
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2013第三届内分泌与代谢大会暨2013第二届糖尿病大会
论文部分内容阅读
Type 1 diabetes (T1D) results from the immune-mediated destruction of insulin-producing B-cells by autoreactive CD4 and CD8 T cells.T1D ranks as the most common chronic childhood disease and its prevalence is increasing.Presently, insulin therapy rescues patients with T1D from certain death but does not satisfactorily prevent long-term chronic complications typically occurring at a relatively young age.Therefore, an early intervention delaying or completely halting disease progression is warranted.
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