Identification of molecular markers for clear cell renal carcinoma(ccRC)is critical for designing therapeutic modalities.Here,we present a comprehensive landscape of the transcriptome profiles of ccRC
The anterior cingulate cortex(ACC) is thought to be key neural substrates underlying emotional responses.Using pain-related conditioned place avoidance models(CPA),we observed that bilateral excitotox
Objective:To establish a stable animal model more approaching clinical cancer pain for further study of the mechanisms.Methods:Adult female Wistar rats were randomly divided into three groups(trail gr
Bufonis Venenum(toad venom)is always used for analgesia in China from ancient to modern times.Bufalin,a non-peptide toxin extracted from Bufonis Venenum,are considered as one of the analgesic componen
Background Cancer has become increasingly prevalent in China over the past few decades.Among symptoms related to the quality of life of cancer patients,pain has commonly been recognized as a most crit
As the most common primary central nervous system tumor,glioma is characterized by high levels of mortality and migration.Unclear boundary with normal brain tissue results in poor treatment.The mammal
Chronic pain is a devastating and distressing experience that can result in mal-adaptive neuroplasticity and negative behavioral consequences,which in turn can result in impaired social function and l