【摘 要】
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Objective:In mitochondrial pathway and death receptor pathway of cell apoptosis,the composition of Bcl-2 family members,especially the ratio of Bcl-2/Bax,is "molecular switch" which starts the cell ap
【机 构】
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College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
【出 处】
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2013国际猪繁殖与呼吸综合征学术研讨会
论文部分内容阅读
Objective:In mitochondrial pathway and death receptor pathway of cell apoptosis,the composition of Bcl-2 family members,especially the ratio of Bcl-2/Bax,is "molecular switch" which starts the cell apoptosis.It was found that American type porcine productive and respiratory syndrome virus(PRRSV),represented by strain ATCC VR-2332,and Europe type PRRSV,represented by strain LV,all could induce cell apoptosis both in vitro and in vivo,and the inducing mechanism was related with virus pathogenesis.In order to accumulate data for PRRSVs pathogenesis research,Bcl-2 and Bax gene expression in PAM infected by PRRSV were detected in this study.
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