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  5. iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafe

iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafe

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：hmxxg
【摘 要】
：
The combination of doxorubicin (DOX) with sorafenib (SOR) has been proved to be an effective strategy to enhance anti-hepatocellular carcinoma (HCC) efficiency However, varied in vivo pharmacokinetic
【作 者】
：
Jinming Zhang Jie Hu Guang Liang Yitao Wang Meiwan Chen 
【机 构】
：
State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,U
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
【关键词】
：
Hepatocellular carcinoma Active targeting Doxorubicin Sorafenib iRGD peptide 
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　　The combination of doxorubicin (DOX) with sorafenib (SOR) has been proved to be an effective strategy to enhance anti-hepatocellular carcinoma (HCC) efficiency However, varied in vivo pharmacokinetic profiles and different endocytosis capacities of these two drugs greatly hinder their current application.
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