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目的分析受检区域骨密度(bone mineral density, BMD)值的差异对原发性骨质疏松症(osteoporosis, OP)诊断的影响。方法回顾在我院进行 BMD检查的 1233例患者,男 414例,女 819例;年龄20-89岁;除外内分泌、肿瘤等疾病及皮质激素治疗史人群。用双能X线骨密度仪(DEXA)对腰椎、髓部及全身进行扫描,测量不同部位的BMD值,采用计算机EXCEL软件进行统计学分析,计量资料进行均数 t检验。结果 L1~2 BMD值比 L2-4低,尤以 40岁以上的女性明显(P<0. 01),髓部BMD值以Ward三角处最低(P<0. 01)。结论腰椎退行性变的干扰影响椎体BMD值的真实性,髋部Ward三角处 BMD值的低下,反映该处骨小梁结构薄弱。 OP的诊断应参考受检区域不同部位的 BMD值,至少进行两个区域的BMD检查对OP的诊断才有意义。
Objective To analyze the influence of different bone mineral density (BMD) in the examined area on the diagnosis of primary osteoporosis (OP). Methods A retrospective study of 1233 patients with BMD in our hospital, 414 males and 819 females, aged 20-89 years; except for endocrine, cancer and other diseases and corticosteroid treatment history of the crowd. The lumbar vertebrae, medullary and whole body were scanned by dual energy X-ray absorptiometry (DEXA). The BMD of different parts were measured. The data were analyzed by computer software EXCEL. The mean t test was used to measure the data. Results The BMD of L1 ~ 2 was lower than that of L2-4, especially in those over 40 years of age (P <0.01). The BMD of marrow in the Ward triangle was the lowest (P <0.01). Conclusions Interference of degenerative lumbar degeneration affects the authenticity of vertebral BMD and the low BMD of Ward triangle, which indicates the weak trabecular structure. The diagnosis of OP should refer to the BMD of different parts of the test area, at least two areas of BMD examination of the OP diagnosis only makes sense.