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The thymic myoid cells were first noted in 1888 by Mayer,who saw them in the frog thymus;they were described as long, spindle-shaped cells showing distinct striations.In human, the myoid cells are rare and located mainly in the medulla and are most abundant in fetal development.The biological role of myoid cells is not yet clear.Raviola & Raviola (1967) suggest that myoid cells played a mechanical role in facilitating lymphocyte passage through the thymus.