Despite decades of studies seeking marker-defined progenitors,a coherent model of dendritic cells(DC)development during hematopoiesis has proven elusive.Usi
Direct sensing of pathogen components is a major trigger of dendritic cell(DC)activation,leading to innate and adaptive immunity.Over the years,we have stud
Epigenetic modifiers play fundamental roles in defining unique cellular identity through the establishment and maintenance of lineagespecific chromatin and
MicroRNAs(miRNAs)are small inhibitory RNAs that regulate the translation of mRNAs.To investigate if this pathway is required for the dendritic cell(DC)devel
Subsets of classical dendritic cells(cDCs)have been defined on the basis of both surface marker patterns and by transcription factor dependence.Evidence of