Regulation of immune cells and cytokines on PMBCs by HBeAg: Molecular mechanisms of HBV persistent i

• 作 者: YongfangJiang;GuozhongGong;
• 机 构: Liver Diseases Research Center, The Second Xiangya Hospital, Central South University, No.139 Middle
• 出 处: 第六届中国医师协会感染科医师大会暨传染病诊治高峰论坛、第十四届中华预防医学会微生态学学术会议
• 发表日期: 2014年期

　　Objective This study was to investigate T-lymphocyte subpopulation profile and the expression of PD-1, TLR3, TLR4, and INF-γon peripheral blood monoctyes(PMBCs) regulated by HBeAg, and to illustrate the relation between HBeAg and persistent infection of HBV.Methods Put blood from the normal person into anticoagulation tube and separate lymphocyte from it.The lymphocytes are divided into four groups and were cultured with various concentration of HBeAg for 72 hours.