Effects of KRAS, BRAF, PIK3CA, and NRAS mutations in Chinese colorectal cancer characteristics and p

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户：k5261715

【摘要】

：

【作者】

：

Yin-Chen Shen Jian-Fei Wang Hong-Ying Yan Shuai Wang Dong-Mei Lin Xiao-Hong Han Yuan-Kai Shi

【机构】

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Department of Medical Oncology,Cancer Institute/Hospital,Peking Union Medical College and Chinese Ac

【出处】

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22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)

【发表日期】

：

2013年7期

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Objective: Mutations in KRAS oncogene are recognized biomarkers that predict lack of response to anti-epidermal growth factor receptor (EGFR) antibody therapies.However,some patients with KRAS wild-type tumors still do not respond.Therefore, other downstream mutations in BRAE PIK3CA, and NRAS should be investigated.

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