Relationship between Polymorphisms in p38beta MAPK and Pre-diabetes in Individuals of Han Chinese De

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：dragon122

【摘要】

：

【作者】

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M.M.Jin X.W.Ma J.Q.Zhang A.M.Dong N.Gu N.Feng X.H.Guo

【机构】

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Geriatric Endocrinology Department of PLA General Hospital, Beijing, 100853, China

【出处】

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2015中国老年医学和老年健康产业大会

【发表日期】

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2015年7期

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OBJECTIVE: The present study aimed to investigate the relationship between p38beta MAPK gene polymorphisms and pre-diabetes in individuals of Han Chinese descent.METHODS: A total of 1,466 non-consanguineous Han Chinese individuals were enrolled in the study.Mass spectrometry was performed to detect three haplotype-tagging single nucleotide polymorphisms (SNPs) of p38beta MAPK.Logistic regression analysis was performed to compare the difference in risk of pre-diabetes and to evaluate the interaction between genotypes and risk factors.

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Relationship between Polymorphisms in p38beta MAPK and Pre-diabetes in Individuals of Han Chinese De

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