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  5. Irregular transcriptome reprogramming probably caused embryo developmental failure of interspecies n

Irregular transcriptome reprogramming probably caused embryo developmental failure of interspecies n

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：wolaixunbao
【摘 要】
：
Methods: Interspecies somatic cell nuclear transfer (iSCNT) has been regarded as a potential alternative in rescuing highly endangered species and can be used as a model for studying nuclear-cytoplasm
【作 者】
：
左永春 郜宇 苏广华 李前忠 李光鹏 
【机 构】
：
哺乳动物生殖生物学及生物技术教育部重点实验室,内蒙古大学,呼和浩特,010070 理论生物物理实验
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
SCNT transcriptome reprogramming embryonic genome activation transcriptional reg 
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　　Methods: Interspecies somatic cell nuclear transfer (iSCNT) has been regarded as a potential alternative in rescuing highly endangered species and can be used as a model for studying nuclear-cytoplasmic interactions.However, iSCNT embryos often fail to produce viable offspring.The alterations of normal molecular mechanisms contributing to extremely poor development is for the most part unknown.
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