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Background To evaluate feasibility and perioperative safety of carotid artery stenting(CAS) for patients for patients coexist with carotid stenosis and contralateral carotid artery occlusion.Methods The clinical data of 52 consecutive patients undergoing carotid artery stenting in Fuwai Hospital from January 2005 to September 2013 were collected and analyzed retrospectively.All patients must meet the following criteria: (1) unilateral common and/or internal carotid stenosis >70%,with contralateral occlusion of common and/or intemal carotid artery;(2) presenting symptoms of neurological ischemia.The reduction of the angiographic diameter stenosis and clinical outcomes of 30 days after stenting including hyperperfusion syndrome,hemodynamic depression,stroke,myocardial infarction and death were assessed.