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In view of the controversies surrounding the glutathione S-transferases (GST) M1/T1-endometriosis association, a meta-analysis of the GSTM1/GSTT1 genetic association studies of endometriosis was performed in Chinese populations.PubMed, Springer Link, OvidSP, and Chinese databases were searched for related studies.A total of nine studies on GSTMl-endometriosis involved 874 cases and 997 controls, and five studies on GSTT1 involved 404 cases and 513 controls were included in this meta-analysis.Overall, the null genotype of GSTM1/GSTT1 was significantly related to endometriosis risk in Chinese populations (GSTM1, OR =2.21, 95% CI: 1.22-4.01; GSTT1, OR =2.31, 95% CI: 1.34-3.99).In subgroup analyses stratified by ethnicity and source of controls, the same results were observed in Chinese Han and population-based studies.The sensitivity analysis confirmed the reliability and stability of the meta-analysis.No publication bias was found among studies by Eggers test.In conclusion, our meta-analysis supports that the GSTM1/GSTT1 null genotype might contribute to individual susceptibility to endometriosis in Chinese populations, especially in Chinese Han.