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  5. Activation of islet 5-HT4 receptor regulates glycemic control through increasing insulin secretion

Activation of islet 5-HT4 receptor regulates glycemic control through increasing insulin secretion

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：xialiaoj
【摘 要】
：
Introduction: Mosapride,an agonist of the 5-HT receptor 4(5-HT4R),is widely used as a prokinetic drug.Meanwhile,it reduces blood glucose of type 2 diabetes.However,whether 5-HT4 receptor is located in
【作 者】
：
Hui Chen Ji Li Jin-Xia Zhu 
【机 构】
：
Department of Physiology and Pathophysiology,School of Basic Medical Science,Capital Medical Univers
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
5-HT4 receptor mosapride insulin islet β cells 
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　　Introduction: Mosapride,an agonist of the 5-HT receptor 4(5-HT4R),is widely used as a prokinetic drug.Meanwhile,it reduces blood glucose of type 2 diabetes.However,whether 5-HT4 receptor is located in the pancreatic islets and whether mosapride can directly stimulate islets insulin secretion remains unknown.
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