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  5. Persistent disruption of mTORC1 in macrophages leads to enhanced nonalcoholic steatohepatitis in mic

Persistent disruption of mTORC1 in macrophages leads to enhanced nonalcoholic steatohepatitis in mic

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：qazmlp159753
【摘 要】
：
Introduction: Nonalcoholic steatohepatitis(NASH),characterized by lipid deposits within hepatocytes,is associated with hepatic injury and inflammation,finally triggering fibrosis,cirrhosis,and hepatoc
【作 者】
：
Wenli Liu Chunjiong Wang Xuejiao Zhang Chenji Ye Ding Ai Yi Zhu 
【机 构】
：
Department of Physiology and Pathophysiology,Tianjin Medical University,Tianjin,China
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
mTORC1 macrophage Nonalcoholic steatohepatitis 
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　　Introduction: Nonalcoholic steatohepatitis(NASH),characterized by lipid deposits within hepatocytes,is associated with hepatic injury and inflammation,finally triggering fibrosis,cirrhosis,and hepatocarcinoma.Recent studies have suggested that mTORC1 participated in the development of hepatic steatosis and NASH.
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