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Background To identify clinic outcome of ticagrelor in therapy patients with acute ST-segment elevation myocardial infarction receiving primary percutaneous coronary intervention.Methods Sixty-two consecutive patients with STEMI receiving primary PCI were included in this study.The clinic characteristics,TIMI refuse after PCI,clinical outcomes after 30 days of patients were compared between patients treatment with ticagrelor (group A 30 cases) and clopidogrel (group B 32 cases).