A New Potential Pathogenic Mutation Has been Found in Human P450 2D6 Gene

来源 :2014第五届国际神经科技大会暨2014首届国际高科技针灸和中西医结合大会 | 被引量 : 0次 | 上传用户：afei137

【摘要】

：

【作者】

：

Lijie Zhang Xuenan Li Lina Da Cui Liu Jiapeng Zhou Yubao Chen

【机构】

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Beijing Computing Center China

【出处】

：

2014第五届国际神经科技大会暨2014首届国际高科技针灸和中西医结合大会

【发表日期】

：

2014年12期

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　　Cytochrome P450 2D6(CYP2D6) enzyme plays an important role in the metabolism of antidepressant, antipsychotie, and antiarrhythmie drugs.Hundreds of drugs have been found to be the substrates of the CYP2D6 enzyme.Quite a lot of studies found that single nuclcotide polymorphisms (SNPs) of CYP2D6 gene should affect the effect of drugs.

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A New Potential Pathogenic Mutation Has been Found in Human P450 2D6 Gene

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