Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of

来源 :2017年第三届岭南国际DMPK论坛 | 被引量 : 0次 | 上传用户：vazumi126

【摘要】

：

Bilirubin-related adverse reactions (ADR, e.g., jaundice and hyperbilirubinemia) induced by herbs rich in certain polyphenolic acids are widely reported.

【作者】

：

Guo Ma Wenyan Chen Qiao Deng Ying Zhang Zhifang Tang Caifu Xue Xiaoqin Liu Weimin Cai Ming Hu

【机构】

：

Department of Clinical Pharmacy, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai

【出处】

：

2017年第三届岭南国际DMPK论坛

【发表日期】

：

2017年10期

【关键词】

：

bilirubin Danshen salvia miltiorrhiza polyphenolic acids salvianolic acid glucur

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　　Bilirubin-related adverse reactions (ADR, e.g., jaundice and hyperbilirubinemia) induced by herbs rich in certain polyphenolic acids are widely reported.

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Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of

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