Expression of BAFF-R but not BAFF as an independent prognostic factor for diffusing large B-cell lym

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户：caoshaohua2009

【摘要】

：

【作者】

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Yu Wang Wen-Qi Jiang Ya-Jun Li Zhi-Ming Li Hui-Lan Rao Jia-Jia Huang Yi Xia Hui-Qiang Huang Tong-Yu Lin Zhong-Zhen Guan

【机构】

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Department of Medical Oncology;State Key Laboratory of Oncology in South China

【出处】

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22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)

【发表日期】

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2013年7期

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Objective: B-cell activation factor (BAFF) and BAFF-receptor(BAFF-R) play crucial roles in the survival and proliferation of malignant B-cells.Limited information exists on the expression profiles and the prognostic roles of BAFF and BAFF-R indiffusing large B-cell lymphoma (DLBCL).Methods: Paraffin-embedded specimens from 136 patients with newly diagnosed DLBCL and treated with R plus CHOP chemotherapy were immunohistochemically examined for BAFF and BAFF-R expressions.The correlation of BAFF and BAFF-R expressions with clinicopathologic characteristics and patient outcome was assessed.

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Expression of BAFF-R but not BAFF as an independent prognostic factor for diffusing large B-cell lym

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