【摘 要】
：
Currently,the standard approach to cancer treatment is chemotherapy combined with radiotherapy and surgical resection [1].However,emerging multidrug resista
【机 构】
：
Key Laboratory of New Drug Delivery System of Chinese Materia Medica,Jiangsu Provincial Academy of C
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
论文部分内容阅读
Currently,the standard approach to cancer treatment is chemotherapy combined with radiotherapy and surgical resection [1].However,emerging multidrug resistance (MDR) usually happens after a couple of chemotherapy courses and becomes a major reason leading to failure in anticancer treatment [2].Fortunately,by right of some MDR-reversible traditional Chinese medicines (TCMs),combinational administration of TCMs and chemotherapeutics provides a promising strategy compared to circumvent MDR.Nevertheless,the dose and ratio of MDR-reversible TCMs and chemotherapeutics are still lack of standardization in clinic treatment.Microemulsion,as a nano-sized drug delivery system for solubilizing water-insoluble components,is usually composed of oil,surfactant and co-surfactant.Inspired by such a composition,several oil-like and MDR-reversible TCMs could be potentially used to fabricate a microemulsion.
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