Traditional Chinese Medicine in Treatment of Metabolic Disorder Induced by Fructose Overconsumption

来源 :2013第三届内分泌与代谢大会暨2013第二届糖尿病大会 | 被引量 : 0次 | 上传用户:peterqiu123
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  In management of the metabolic syndrome, the traditional Chinese medicine (TCM) is an excellent representative in alternative and complementary medicines with a complete theory system and substantial herb remedies.However, their underlying mechanisms of actions are still largely unknown.Strong evidence suggests that consumption of diets high in fructose results in fatty liver, dyslipidemia,insulin resistance, and obesity in animals and humans.Our recent findings suggest that in rats,modulation of the hepatic ChREBP-mediated de novo fatty acid biosynthesis is involved in amelioration of fructose-induced fatty liver and hypertriglyceridemia by the treatment with the extract of ginger or Salacia oblonga root.
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