Precondition and Postcondition the Functionally Impaired Diabetic Heart against Ischemia-reperfusion

来源 :2013第三届内分泌与代谢大会暨2013第二届糖尿病大会 | 被引量 : 0次 | 上传用户:yangzb5
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Brief episodes of ischemia and reperfusion given before prolonged ischemia protect the myocardium, a phenomenon referred to as ischemic preconditioning (IPC).Although effective, IPC requires access to the coronary vessels which is not feasible in the majority of cases.Subsequently, attention has focused on modifying events occurring at the time of myocardial reperfusion (i.e., ischemic postconditioning, IPostC).IPC and IPostC activate similar protective mechanisms in the heart.
其他文献
The db/db mice are perfect animal models of type 2 diabetes that have been widely used.Their phenotypes of severe obesity, hyperphagia, polydipsia, and polyuria are due to a spontaneous mutation of le
会议
At least six major steps are required for secreted thyroid hormone (TH) to exert its action on target tissues.For three of these steps, human gene mutations and specific phenotypes have been identifie
会议
Metabolic diseases consist of, typically hereditary, heterogeneous groups of health conditions that arise from critical interruption in metabolic pathways.These conditions are categorized into two typ
会议
It has been widely accepted that calorie restriction can expend aging in various animal models.However, caloric restriction, in fact, does nothing on aging itself, but simply relieves stress.Stress ma
会议
Friedreich ataxia (FRDA) is an inherited neurodegenerative disease caused by frataxin (FXN) deficiency due to the insertion of GAA triplet repeats within the first intron of FXN gene.FXN, a highly con
会议
Preeclampsia is a complex multisystem disorder of pregnancy where oxidative stress plays an important etiological role.The importance of selenium in the synthesis of endogenous antioxidants is well do
会议
A high carbohydrate intake is important for endurance athletes because endurance exercise performance is limited when intramuscular glycogen is depleted.Carbohydrates can be classified by their glycem
会议
Bovine milk has been a staple of the human diet for thousands of years and represents one of the most important agricultural commodities in regards to human nutrition.Milk provides a large variety of
会议
Obesity is arguably the most threatening world health epidemic of the modem era.Despite countless years of research, recommendations to improve prognosis are still general and population basedto balan
会议
Exercise training is known to increase fat utilization during exercise.Diets containing antioxidants and branch chain amino acids (BCAAs) are also reported to have potential effects on fat utilization
会议