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  5. Pancreatic synthesized dopamine elicits a somatostatin-dependent inhibition of insulin secretion

Pancreatic synthesized dopamine elicits a somatostatin-dependent inhibition of insulin secretion

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：wq446395427
【摘 要】
：
Backgrounds and aims: Pancreatic dopamine regulates insulin secretion in an autocrine manner,but the tyrosine hydroxylase(TH),a time-limiting enzyme for dopamine synthesis,is not present in islet.How
【作 者】
：
Feng Hong Hui Chen Ji Li Jin-Xia Zhu 
【机 构】
：
Department of Physiology and Pathophysiology,School of Basic Medicinal Sciences,Capital Medical Univ
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
Pancreas dopamine synthesis D2 distribution indirectly regulation 
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　　Backgrounds and aims: Pancreatic dopamine regulates insulin secretion in an autocrine manner,but the tyrosine hydroxylase(TH),a time-limiting enzyme for dopamine synthesis,is not present in islet.How is the dopamine synthesized in pancreas? Dopamine receptor 2(D2)is exclusively distributed in the somatostatin(SST)-secreting δ cells,not insulin(INS)-secreting β cells in rat pancreatic islets.
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