【摘 要】
：
目的:本实验给予去卵巢大鼠异丙肾上腺素制作心肌损伤及心功能异常模型,探讨雌激素通过调节兴奋性G(Gαs)蛋白-环磷酸腺苷(cAMP)信号通路纠正儿茶酚胺导致的心功能异常的机制.方法:成年雌性大鼠随机分为5组:假手术组、去卵巢组、去卵巢后补充雌激素组、去卵巢后注射异丙肾上腺素组和去卵巢后补充雌激素并注射异丙肾上腺素组.
【机 构】
：
徐州医学院生理学教研室,江苏徐州221000
【出 处】
：
中国病理生理学会心血管专业委员会第十五届学术大会暨国际心脏研究会中国分会第十二届学术大会
论文部分内容阅读
目的:本实验给予去卵巢大鼠异丙肾上腺素制作心肌损伤及心功能异常模型,探讨雌激素通过调节兴奋性G(Gαs)蛋白-环磷酸腺苷(cAMP)信号通路纠正儿茶酚胺导致的心功能异常的机制.方法:成年雌性大鼠随机分为5组:假手术组、去卵巢组、去卵巢后补充雌激素组、去卵巢后注射异丙肾上腺素组和去卵巢后补充雌激素并注射异丙肾上腺素组.
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