Haploinsufficiency of a novel gene on 3p26.1, SMDD1,cause autosomal-dominant dentin dysplasia type Ⅰ

• 作 者: FuXiong[1]ZhisongJi[1]YanhuiLiu[2]YuZhang[1]LinglingHu[1]QiYang[1]QinweiQiu[1]LingfengZhao[3]DongChen[4]ZhihuiTian[5]XuanShang[1]LeitaoZhang[5]XiaofengWei[1]CuixianLiu[1]QiuxiaYu[1]MeichaoZhang[6]Jing
• 机 构: Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University,Guangz
• 出 处: 第十四次全国医学遗传学学术会议
• 发表日期: 2015年期

　　The hereditary dentin defects, dentinogenesis imperfecta(DGI)and dentin dysplasia (DD) comprise a group of autosomal-dominant genetic conditions and the molecular basis of such dental disorders in all sub-groups except for DD Type Ⅰ (DDI)is linked to mutations in dentin sialophospho-protein gene (DSPP).