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Background Left ventricular (LV) hemodynamic condition and mechanical function are major components of overall cardiac function.Traditional evaluation of hemodynamics with Doppler ultrasound is, however, angle dependent and limited in the spatial characterization of intraventricular flow pattern.With the development of Contrast echo, it is visible that blood flow forms intraventricular vortex ring during early LV filling, which has been shown to optimize the diastolic fluid dynamics and the efficiency of systolic ejection.Vortex formation time (VFT) was introduced to characterize the optimal condition of vortex ring formation.Reduced diastolic suction after acute myocardial infarction (AMI) might lead to abnormal LV vortex ring formation.Less study was done on the hemodynamic changes in AMI assessed by VFT and its correlation with future left ventricular remodeling.We sought to investigate hemodynamic changes in AMI patients undergoing primary percutaneous coronary intervention (PCI) with VFT and its correlations with myocardial function and one-year remodeling.