Identification of Long non-coding RNA biomarker of human breast cancer

来源 :第七届全国生物信息学与系统生物学学术大会 | 被引量 : 0次 | 上传用户：hou189

【摘要】

：

【作者】

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常志强张强严自创许艳

【机构】

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生物信息科学与技术学院,哈尔滨医科大学,哈尔滨150081

【出处】

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第七届全国生物信息学与系统生物学学术大会

【发表日期】

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2016年8期

【关键词】

：

Breast cancer Differential expression Differential co-expression lncRNA biomarke

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　　Background: Accumulating evidence indicates long non-coding RNAs (lncRNAs) have shown promise as cancer biomarkers,and little lncRNAs and their function associated with breast cancer (BC) were discovered.Method: We re-annotated and filtered the lncRNA profile of 616 BC and 113 normal samples,applied DESeq2 to discover the differential expressed lncRNAs (DELs),and then provided a framework for discovering differential co-expressed lncRNA-lncRNAs (DCLLs).

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