【摘 要】
：
Bisphosphonates are now commonly prescribed for the treatment of osteoporosis and bone cancers.Bisphosphonateinduced osteronecrosis of the jaws (BIONJ) refers to a condition characterized by persisted
【机 构】
：
Department of Oral and Maxillofacial Surgery,Faculty of Dentistry,Khon Kaen University,Thailand
【出 处】
：
11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲
论文部分内容阅读
Bisphosphonates are now commonly prescribed for the treatment of osteoporosis and bone cancers.Bisphosphonateinduced osteronecrosis of the jaws (BIONJ) refers to a condition characterized by persisted necrosis and exposure of the bone in the jaws of patients who had been experienced or currently taking a bisphosphonate without head and neck radiation therapy.Risedronate (Actonel(r)), an oral form bisphosphonate, has become more prevalent but discover few reports ofBIONJ.A seventy two years old woman came to our department with an unhealed socket after removal of＃ 46 for 3 months.She had been treated osteoporosis with weekly Risedronate for 2 years.(Prednisolone and metrotrexate have started since last year) Previously medical history was rheumatoid arthritis, osteoporosis and a current history ofprednisolone and metrotrexate use.The patient was performed four times local debridement and sequestrectomy with primary closure under local anesthesia, antibiotic was prescribed and also cessation ofrisedronate, metrotrexate, prednisolone.The wound was completely healed 6 months after first operation.This patient had multiple problems and treated by various medications, which increased risk of BRONJ.Multidisciplinary approach was important to reach the success of treatment while medications adjustment and surgical treatment would have to be synchronized.
其他文献
Objective: This article aimed to achieved a surgery planning that used digital medical technology to repair a transmedian mandibular defect, and designed the digital model of titanium plate for mandib
Objective: The Eagles syndrome is characterized by a variety of symptoms including throat pain, pharyngeal foreign body sensation, dysphagia, referred otalgia, and neck and throat pain exacerbated by
Objective: To systematically assess the relevance of survivin expression and risks of Oral squamous cell Carcinoma (OSCC) by performing a meta-analysis.Methods: We searched the Web of Science, Pubmed,
Objective: We investigated the effect of exogenous ceramide on endoplasmic reticulum stress of ACCs, and the possible mechanism for cancer cell death.Methods: Reverse-transcription PCR and Real-time P
Background: Migration and invasion of tumor cells are essential prerequisites for the formation of metastasis in malignant diseases.In the previous study, we have reported that CCR7 regulate the mobil
Background: Diagnosis of mandibular invasion caused by head and neck cancers is critical for treatment.We performed a meta-analysis to determine the diagnostic efficacy of MR for distinguishing mandib
Objective: Squamous cell carcinoma (SCC), such as gingival carcinoma, has been recognized to display a tendency of bone destruction at the late stage of the disease.However, the mechanism involved in
Objective: Salivary adenoid cystic carcinoma (SACC) is one of the most common salivary gland carcinoma with poor prognosis and frequently metastasizes to distant organs, especially to lung.We previous
Objective: Aggressive resection of a large mandibular cystic ameloblastoma may cause severe deformity and dysfunction, while simple enucleation may carry a high risk of recurrence.The purpose of this
This study aimed to describe a newly discovered lesion — a fibro-epithelial polyp surrounding the orifice of Stensens duct.The clinical data of three patients (one male and two females) was collected