CCR7 Regulates Cell Migration and Invasion through MAPKs in Metastatic Squamous Cell Carcinoma of He

来源 :11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲 | 被引量 : 0次 | 上传用户：ploveye999

【摘要】

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【作者】

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Fa-yu Liu Jawad Safda Zhen-ning Li Qi-gen Fang Xu Zhang Zhong-fei Xu Chang-fu Sun

【机构】

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Department of Oromaxillofacial-Head & Neck Surgery;Department of Oral and Maxillofacial Surgery,Scho

【出处】

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11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲

【发表日期】

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2014年3期

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Background: Migration and invasion of tumor cells are essential prerequisites for the formation of metastasis in malignant diseases.In the previous study, we have reported that CCR7 regulate the mobile ability of squamous cancer cells of head and neck (SCCHN) through several pathways, such as integrin and cdc42.In this study, we want to identify the connection between CCR7 and Mitogen-activated protein kinases (MAPK) family members, and their influence on cell invasion and migration in metastatic SCCHN cells.

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CCR7 Regulates Cell Migration and Invasion through MAPKs in Metastatic Squamous Cell Carcinoma of He

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