FKBP4 Causing Glucocorticoid Resistance (GR) is a Novel Reason for Premature Adrenarche and Ovarian

来源 :2011年第一届内分泌与代谢大会 | 被引量 : 0次 | 上传用户：yaki84

【摘要】

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【作者】

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Svetlana Ten

【机构】

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State University of New York Downstate Medical Center USA

【出处】

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2011年第一届内分泌与代谢大会

【发表日期】

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2011年3期

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　　We screened 67 children with Premature adrenarche(PA) and 98 adolescents with PCOS and metabolic syndrome and found that around 10-12 % of cases are secondary to glucocorticoid resistance.PA occurs before age g yr in girls and 9 yr in boys.PA can be a normal variant of maturation, precursor of metabolic syndrome, NC-CAH, tumor, Cushings disease and previously was considered to be a rare sign of GR.There has been only two reports of GR presenting as PA.

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FKBP4 Causing Glucocorticoid Resistance (GR) is a Novel Reason for Premature Adrenarche and Ovarian

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