【摘 要】
：
The control of saliva secretion is mainly under autonomic nervous control.Pituitary adenylate cyclase-activating polypeptide (PACAP) is now recognized as the multi-functional neuropeptide in various o
【机 构】
：
Department of Oral Anatomy and Developmental Biology,Showa University School of Dentistry;yokohama G
【出 处】
：
11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲
论文部分内容阅读
The control of saliva secretion is mainly under autonomic nervous control.Pituitary adenylate cyclase-activating polypeptide (PACAP) is now recognized as the multi-functional neuropeptide in various organs.Our previous study indicated the localization of PAC1R in adult mouse major salivary glands.In this study, we examined the ontogenic expression of PAC1R in mouse salivary glands.Salivary glands at 0, 3, 5, 7, 14 and 21 days postnatal male C57BL/6 mice were used for the immunohistochemical detection of PAC 1R.In the parotid gland, the acinus was not clearly formed and PAC1R was not detected until 14 days after birth.At 14 days, PAC1R was detected in the striated duct.In the sublingual gland, the acinus and duct were formed at 0 day after birth.PAC1R was constantly expressed in the striated duct from the 0 day postnatal stage.In the case of the submandibular gland, the granular duct was not clearly identified and PAC1R was localized in the striated duct and first detected in the striated duct until 21 days after birth.After 21 days, PAC1R was clearly detected at pillar cells in the granular duct.Some of cells in the duct showed intense immunoreactions of PAC 1R.These results indicated that PAC 1R was expressed in the striated duct of parotid and sublingual glands and that the localization of PAC 1R was changed with the formation of granular duct.A precise study may be necessary to clarify the function of pillar cells by examining the shift of PAC1R-positive cells in the submandibular gland.
其他文献
Objectives: To discuss coronal incision approach for the management of tumors in the pterygopalatine and infratemporal fossa.Methord: A retrospective review of 7 cases with tumors in pterygopalatine a
Objective: To study the roles of miR-300 in regulating EMT.Methods: The expression levels of miR-300 were examined in epithelial carcinoma cells that underwent an EMT using quantitative reverse transc
Objective: To examine the expression of full-length spleen tyrosine kinase (Syk) mRNA and protein in human oral squamous cell carcinoma (OSCC) and normal oral mucosa tissues, and to assess its effects
Both alpha-enolase and myc promoter-binding protein-1 (MBP-1) originate from a single gene ENO1 through alternative translational starting sites.Alpha-enolase is a glycolytic enzyme that catalyzes the
Objective: To review our experience on the difference in management and treatment outcomes of aggressive fibromatosis of the head and neck region in children and adults particularly emphasizing on rol
Objective: A retrospective study of clinical data for 200 cases of primary parotid gland tumors in the day surgery ward have been done, in order for us doctors to get some useful information of the pr
TSGCT is a rare, benign, idiopathic proliferative destructive disease of the synovium.It tends to arise in large joints like knee and ankle and rarely in TMJ.Destructive nature of TSGCT required immed
Objective: To analyze various CT, MRI and ultrasound features and its values in diagnosis and surgical therapy of lingual squamous cell carcinoma.Methods: After searching through the pathology data ba
Background: Patients with advanced head and neck squamous cell carcinoma (HNSCC) show poor prognosis to current therapy and tumor recurrence and metastasis are frequently observed.The discovery of can
Objective: Since the first report of osteonecrosis of the jaw associated with bisphosphonates administration in 2003,there have been many efforts to understand the nature of disease.This study was to