【摘 要】
：
Osteoarthritis (OA),or cartilage degeneration,is the most common form of arthritis.An important feature of the disease is the progressive destruction of art
【机 构】
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The Netherlands Organization for Applied Scientific Research Netherlands
【出 处】
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中国上海第七届国际新药发明科技年会
论文部分内容阅读
Osteoarthritis (OA),or cartilage degeneration,is the most common form of arthritis.An important feature of the disease is the progressive destruction of articular tissues,resulting in impaired movement,pain and ultimately disability.Despite the growing knowledge on the pathogenesis of OA,its etiology is still not clear and effective disease-modifying treatment is lacking.Diagnosis of OA is currently based on clinical symptoms in combination with radiology.Imaging modalities to monitor the disease mainly images bone and are relatively insensitive (radiology) or still in development for full-fledged implementation (MRI).Alternative methods are therefore needed in order to detect osteoarthritic changes in a quantitative,reliable,and sensitive manner.
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