Improvement of reconstruction of microbial community with multiple 16S rRNA regions

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：alivealive

【摘要】

：

　　It has long been recognized that the "universal" 16S rRNA gene primers commonly used in microbial community surveys are inherently biased toward some taxa.I

【作者】

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王圣钦孙蓓丽陆祖宏

【机构】

：

生物电子学国家重点实验室,生物科学与医学工程学院,东南大学,南京,210096生物电子学国家重点实验室,生物科学与医学工程学院,东南大学,南京,210096;生物医学工程系,工学院,北京大学,北京,1

【出处】

：

第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会

【发表日期】

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2014年10期

【关键词】

：

16S rRNA High throughput sequencing Hyper-variable region

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　　It has long been recognized that the "universal" 16S rRNA gene primers commonly used in microbial community surveys are inherently biased toward some taxa.In our previous work, we found that genera have their own best genus-specific amplicons for genus assignment, which sometimes is not located in hyper variable regions (HVRs).

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Improvement of reconstruction of microbial community with multiple 16S rRNA regions

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