Evaluation and application of barcodes in sequencing-by-ligation platform

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：kill5678

【摘要】

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　　Background: The multiplexing becomes one of the major limitations of the next-generation sequencing platforms in application to low complexity samples, incl

【作者】

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涂景葛芹玉王圣钦王磊陆祖宏

【机构】

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生物电子学国家重点实验室,生物科学与医学工程学院,东南大学,南京,210096儿童发展与学习科学教育部重点实验室,学习科学研究中心,东南大学,南京,210096生物电子学国家重点实验室,生物科学与医学

【出处】

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第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会

【发表日期】

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2014年10期

【关键词】

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barcode next-generation sequencing miRNA

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　　Background: The multiplexing becomes one of the major limitations of the next-generation sequencing platforms in application to low complexity samples, including the sequencing-by-ligation platforms.The application of barcodes mitigates this limitation but becomes less practicable when the sample number is large.

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Evaluation and application of barcodes in sequencing-by-ligation platform

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